Double-blind Trial with Propranolol and Alprenolol on Angina Pectoris

Double-blind Trial of Propranolol (inderal) in Angina Pectoris.

Double-blind three-dose trial of oral alprenolol in angina pectoris.

Prophylactic treatment of angina pectoris. A double-blind cross-over comparison of alprenolol and pentanitrol.

Twenty-one patients with angina pectoris took part in a double-blind cross-over comparison of alprenolol (an adrenergic beta-blocker), pentanitrol (pentaerythritol tetranitrate), and placebo. Two-thirds of the patients were clinically improved on alprenolol 100 mg. four times daily, which was found to be significantly better than pentanitrol 30 mg. four times daily and placebo. There was also a...

Trasicor in angina pectoris: a double-blind trial.

Eighteen patients entered a double-blind trial of the beta-adrenergic blocking drug Trasicor in the treatment of angina pectoris. Six patients had to be withdrawn from the trial when substitution of placebo for Trasicor caused severe exacerbation of angina attacks. In these cases the frequency and severity of angina attacks fell to a minimum when Trasicor was re-established. A further 10 patien...

Practolol in treatment of angina pectoris. A double-blind trial.

Twenty-four patients with angina pectoris entered a double-blind trial of the cardioselective beta-adrenergic blocking agent practolol. Seventeen experienced less angina and consumed fewer glyceryl trinitrate tablets when on the active preparation. There was also a decrease in the mean number of attacks suffered by patients while on practolol and a reduction in the number of glyceryl trinitrate...